Role of Inflammatory Markers in Predicting Severity and Outcome in COVID-19 Patients Attending a Tertiary Care Institute of Tamil Nadu

Background:Severe acute respiratory syndrome Coronavirus 2 (SARS-COV 2) infection elicits an inflammatory response which is responsible for severe clinical manifestations, disease progression and, poor outcomes.Objectives: This study aims to assess the pattern of elevation markers in COVID-19 and determine their association with clinical, radiological severity outcome COVID 19.Methodology: a retrospective single-center cross-sectional conducted at Chettinad Hospital Research Institute, tertiary care Tamil Nadu, India, encompassing cohort 1220 patients. The source population was all cases admitted hospital confirmed diagnosis using RT PCR. data obtained from patient’s case sheets laboratory investigations electronic management system. on admission, baseline characteristics, co-morbid illnesses, presenting complaints, vitals, like D-dimer, C-reactive protein IL-6, Serum ferritin, Lactate dehydrogenase were collected. coded analysed.Results: Diabetes hypertension found be most common comorbidities population; females more affected than males. Fever cough are symptoms. patients have significant severity. D-dimer having strong correlation any point time. CRP, ferritin also showed COVID-19.Conclusion:Our suggests time hospitalized patient as promising marker same. IL-6 next best followed by CRP ferritin. LDH least one among these.